I just saw a commercial for a new game for the Nintendo DS entitled "Super Princess Peach" according to the commercial, this time the princess is gonna be on a mission to rescue Mario and Luigi. Most of the commercial was a bunch of little girls in princess outfits going through a bootcamp-style obstacle course, culminating with them stopping when confronted by a tall barricade, and blowing it up just by concentrating for a moment. There was also a little actual gameplay footage shown, where the Princess flys a little, and attacks monsters with water and fire attacks.
I know this game will probably rank low on the ubergirl scale, but I think it's significant since up until now, Mario and Luigi have usually been tasked with rescuing HER but now the tables are turned.